• Manufacturer: Allergan
  • Substance: botulinum toxin
  • Strength: 100 units


This brand name product contains botulinum toxin, which belongs to the assortment of muscle relaxants with a peripheral action mechanism. It has the force to block the release of acetylcholine in peripheral presynaptic cholinergic nerve endings because it can cleave SNAP-25. After the injection in the dermal tissue, the toxin rapidly absorbed through the cell surface receptors. Then the toxin transmits further through the membrane plasma due to receptors. After that, the toxin released into the cytosol, and in the process, the release of acetylcholine gradually slowed down. The clinical effect of Botox appears on the second or third day. The best effect can be reached after five to six weeks after the treatment session. The recovery process after the injection takes up to 13 weeks since the nerve endings grow and restore communication with the final plate. The visible effect after the injection (50 units —Allergan) in the armpits can last 8-12 months or more (in 30% of patients).


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